Noni Helps in Growth Hormone Deficiency

Growth hormone deficiency (GHD) is a medical condition which is caused by complications arising in the pituitary gland, in which the body does not produce enough growth hormone (GH). Growth hormone, also called somatropin, is a polypeptide hormone which stimulates growth and cell reproduction.

Growth hormone deficiency has a variety of different destructive effects at different ages; for example, in newborn, the primary appearances may be hypoglycemia or micropenis, while in later infancy and childhood, growth failure is more likely. Deficiency in adults is rare, but may feature diminished lean body mass, poor bone density, and a number of physical and psychological symptoms. Psychological symptoms include poor memory, social withdrawal, and depression, while physical symptoms may include loss of strength, stamina, and musculature. Other hormonal or glandular disorders frequently coincide with diminished growth hormone production.

The most common cause of GHD (representing two-thirds of cases) are pituitary and parasellar tumors. The origin of adult GHD may be congenital or acquired. Of those adult GHD that are acquired, roughly 15% are idiopathic, 50% are from pituitary tumors, 20% from extra pituitary tumors, and 5% from infiltrative or inflammatory lesions.

GH deficiency can be treated through growth hormone replacement, injections of growth hormone, or radiation or surgical treatment of tumors.

Role of Noni

Noni fruit contains a Xeronine that is able to modify the molecular structure of proteins. Thus Xeronine has wide range of biological activities. When a protein such as an enzyme, receptor, or signal transducer is not in the appropriate conformation, it will not work properly. Xeronine will interact with the protein and make it fold into its proper formation. The result is a properly functioning protein. Whenever a problem arises in the cell due to a protein structural problem, Xeronine’s presence would be beneficial.